Non-small cell lung cancer patients had a median OS of 6.43 months (95% CI: 3.45–9.43) and 27 out of 38 received WBRT, this being the only factor associated with increased OS (HR of death if WBRT omitted=3.07, 95% CI: 1.08–8.69, P=0.035) regardless of incorporating MIP staining or the DS-GPA factors. The gene discussed is MIP; the disease is non-small cell lung carcinoma.