PSMB8 and infection: Although no difference in the overall approximate survival rate was observed between WT and β5i/LMP7-/- mice, mice deficient in the β5i/LMP7 subunit and hence in fully functional i-proteasomes died at earlier time points with an enhanced mortality during the first 108 h of infection, showing an approximate death rate of about 12% in WT versus about 23.5% in β5i/LMP7-/- mice.