CRP and coronary artery disorder: In conclusion, it should be noted that our results support the hypothesis ofthe influence of the SAA1, CRP,CCL2, CCR2, and CX3CR1 genepolymorphisms on the processes that play an important role in CHD pathogenesis.We also demonstrated that allelic variants of the SAA1 andCRP genes can have both a negative and positive effect on thedevelopment of the disease depending on the genetic environment, whichillustrates the thesis of a complex nonlinear interaction of the studiedfactors and does not contradict the results obtained in other studies.