Choi D et al. studied the expression of CD24 and CD133 with IHC method on colorectal adenocarcinoma and showed an association between the expression of CD24 and CD133 with tumor differentiation, as well as the relation of CD133 with male gender and depth of tumor invasion (9) these findings were not found in our study. This evidence concerns the gene PROM1 and colorectal adenocarcinoma.