As transfected channels and subunitsdo not necessarily emulate in vivo expression, we also tested the effect ofcompound 8 and nifedipine on endogenous CaV1.3 present in H295R cellsand primary adrenal cells acquired from adrenals containing an APA (both tumour andadjacent normal adrenal tissues). This evidence concerns the gene CACNA1D and neoplasm.