While babies with ALSG or LADD do not display apparent lung defects, adult patients with heterozygous loss of function of FGF10 exhibit a significant decrease in inspiratory vital capacity (IVC), forced expiratory volume in one second (FEV1), and FEV1/IVC quota compared to non-carrier siblings and predicted reference values [51]. The gene discussed is FGF10; the disease is LADD syndrome.