PLAUR and cancer: PLAUR (i) expression is regulated by KLF4 [34] and is upregulated in cancer cells [35, 36] and in response to pro-inflammatory conditions [37], (ii) facilitates neutrophil recruitment in response to bacterial infection [38], (iii) facilitates clearance of Borrelia infection [39], and (iv) interacts with multiple partners including vitronectin and different integrins.