TLR4 and allergic asthma: Figure 3A illustrates the number of genes associated with asthma using these methods. There is an inverse correlation between these data sources and the number of genes, i.e. a large number of publications are associated with relatively few genes: 13 genes (Ccl11, Ccl5, Cd14, Cysltr1, Gstm1, Ifng, Il10, Il13, Il33, Il4, Il4ra, Tlr2, and Tlr4) account for approximately 1/3 of the articles published on asthma for these 933 genes (Fig. 3). In our dataset, there are 493 genes (Fig. 3B) that are as yet unrelated to asthma and belong to the acute allergic asthma “ignorome”.