Notably, neuroblastoma patients with moderate (2+) or high (3+) expression of XAF1 (15 out of 86 cases) showed a better survival outcome (86.7%, 13 out of 15 cases) as compared to those with complete loss or low XAF1 expression (70.4%, 50 out of 71 cases), suggesting a possible correlation between XAF1 expression and survival outcome (Figure 2B). The gene discussed is XAF1; the disease is neuroblastoma.