Several other authors have also investigated the radiosensitizing potential of various HADCi in terms of their capacity to reduce the repair of damage in different tumor lines, significantly reducing the expression of RAD51, an important protein for the HR repair pathways [53, 61], and of Ku86, Ku70 and DNA-PKcs, important proteins for the NHEJ repair pathway [54, 62, 63]. The gene discussed is PRKDC; the disease is neoplasm.