Levels of 6Ckine and IGFBP-2 or IL-1R4/ST2 in SP patients were significantly higher from day 1 or day 3 and on as compared with those in controls and in SP-ARDS patients, as shown in Fig. 2 (P < 0.05 or less). The gene discussed is IGFBP2; the disease is acute respiratory distress syndrome.