To characterize whether IL-6 is capable of inducing an EMT phenotype to promote lung cancer, we investigated the gene and protein expression of the epithelial marker E-cadherin and the mesenchymal marker vimentin and found an expression pattern of E-cadherin repression (Fig. 5a) and concomitant induction of vimentin (Fig. 5b) in lung cancer cells as compared with control cells. This evidence concerns the gene VIM and lung cancer.