Among cancer indications in TCGA with ≥3 patients harboring CN gains in SRSF1 (BRCA, KIRP, SARC, SKCM, and UCEC), uterine corpus endometrial carcinoma (UCEC) was the only indication with a correlation between SRSF1 CN gain and poor survival (log-rank test p = 0.003), though the patient number with a CN gain group was highly unbalanced compared to those without (n = 8 vs. n = 437, respectively), likely driving the low p-value. This evidence concerns the gene SRSF1 and cancer.