Additionally, the concordance between the top 100 genes harboring the most recurrent nonsilent somatic SNVs or indels in this study and a recent WES study of Asian SCLC patients (Japanese; n = 51) was 62% (S2 Table), with strong consistency of recurrence prevalence in TP53 (82% vs. 80%), RB1 (47% vs. 39%), and CSMD3 (47% vs. 37%), among other genes, between the two studies [5]. This evidence concerns the gene RB1 and small cell lung carcinoma.