There is no consensus on androgen receptor's (AR) role in SCZ;116, 117, 118AR variants are associated with obesity in T2D men,119 and androgens may be implicated in beta-cell dysfunction.120 Thus, AR gene may confer risk for both T2D and SCZ, and its role in SCZ–T2D comorbidity cannot be ruled out. The gene discussed is AR; the disease is obesity due to melanocortin 4 receptor deficiency.