Apolipoprotein D (APOD) is associated to T2D,99 but its implicated role in SCZ is not confirmed in all studies.100 Wolfram syndrome 1 (WFS1) confers risk to T2D,101 and, despite high mental disorder prevalence (but not SCZ) in patients with Wolfram syndrome, WFS1 role in SCZ is not supported.102, 103. This evidence concerns the gene APOD and psychiatric disorder.