In conclusion, our findings demonstrate that EZH2 promotes cell proliferation and tumor formation in cervical cancer cells by activating the Wnt/β-catenin pathway and reveal a molecular mechanism by which EZH2 mediates the transcriptional repression of GSK-3β and TP53, which are inhibitors of the Wnt/β-catenin pathway (Figure 7). Here, EZH2 is linked to neoplasm.