Type I is associated with MET alterations, whereas Type II tumours are characterized by cyclin-dependent kinase Inhibitor 2A (CDKN2A) silencing, SETD2 mutations, transcription factor E3 (TFE3) fusions and increased expression of the nuclear factor-like 2 (NRF2)–antioxidant response element pathway [15]. Here, TFE3 is linked to neoplasm.