ACVR2B and Wilms tumor: Senanayake et al. [19] reported that miR-192, miR-215 and miR-194 had significantly lower expression in nephroblastomas, and they identified the target as activating receptor type 2B (ACVR2B), indicating that downregulation of miR-215 may affect an important step in the pathogenesis of renal childhood neoplasms.