Wang et al. showed that recombinant human augmenter of liver regeneration promoted liver regeneration, attenuated liver injury, increased overall survival, and suppressed immunological responses in d-galactosamine (GaIN) induced acute liver failure rats, along with significantly reduced IL-1β of serum and ascites, suggesting an important role of IL-1β in liver regeneration [31]. The gene discussed is IL1B; the disease is acute liver failure.