Recently, our group investigated its prevalence using quantitative real-time RT-PCR in a series of 203 normal karyotype AML patients (NK-AML) at diagnosis, and reported that high CIP2A expression is a is a recurrent event in this AML subgroup (51/203, 25%), with a poor prognostic impact in the overall survival of NK-AML cases (40). Here, CIP2A is linked to acute myeloid leukemia.