In contrast to CtBP2, similar investigation on CtBP1 expression demonstrated a relatively higher expression level in all EBV-infected cells irrespective of EBNA-3 expression (White et al., 2010; Skalska et al., 2013), signifying a differential regulation pattern of CtBP1 and CtBP2 in response to EBV infection. The gene discussed is CTBP1; the disease is Epstein-Barr virus infection.