PDLIM7 and Burkitt lymphoma: However, it has been suggested that a subset of in vitro generated BL clones may retain the expression of EBNA-3 proteins in either a Wp-restricted latency program with EBNA-2 deletion or a rare EBNA-2(+)/LMP-1(−) latency associated program, indicating the importance of EBNA-3 proteins, in particular EBNA-3A and -3C, in regulating BL pathogenesis thorough blocking cellular apoptosis (Kelly et al., 2005, 2006; Anderton et al., 2008).