NFKB1 and colorectal carcinoma: The aims of this work were firstly, to demonstrate that the NF-κB pathway was hyper-activated in CRC cells with acquired resistance to OXA and to evaluate whether the combined treatment of Curcumin and OXA could revert this phenotype and secondly, to find one or more predictive markers for the effectiveness of this combination that could be used in the selection of patients with high probability to respond to this treatment.