CD8A and toxoplasmosis: Toxoplasma gondii ROP18 protein is considered a promising candidate target for vaccination against acute toxoplasmosis in mice [16, 19], and a specific CD8+ T-cell response against TgROP18-derived peptides has also been observed in patients with chronic asymptomatic toxoplasmosis, suggesting the potential immunogenicity of TgROP18 in patients with chronic toxoplasmosis [40].