Patients who were non-smokers and having a CYP1A1 m1 (T/C) (OR 1.82, 95 % CI 1.08, 3.07) and CYP1A1 m2 (A/G) (OR 12.39 95 % CI 6.53, 23.51) genotypes had an increased lung cancer. The gene discussed is CYP1A1; the disease is lung cancer.