Corella et al. studied the genetic predisposition to present increased fasting glucose, total cholesterol, LDL cholesterol, triglyceride (TG) concentrations, and stroke incidence in homozygote individuals for the T allele of the rs7903146 polymorphism in the TCF7L2 (transcription factor 7-like 2) gene. The gene discussed is TCF7L2; the disease is Stroke.