WNK2 and infection: The C. trachomatis-induced inflammation reaction is mediated by signaling pathways in the host cell that are triggered after infection, including the mitogen-activated protein kinase (MAPK) pathway, Janus-activated kinase-signal transducer and activator of transcription (JAK/STAT) pathway, and nuclear factor-kappa B (NF-κB) pathway, among others.