One study reported that patients with NASH had significantly higher serum TNF-α than those with simple steatosis, while another recent study further stated that patients with NASH had higher levels of TNF-α messenger ribonucleic acid (mRNA) than healthy controls with a sensitivity 66.7% and a specificity 74.1% [16]. The gene discussed is TNF; the disease is metabolic dysfunction-associated steatohepatitis.