As the peptide inhibitors used also have effect on other caspases apart from CASP7, which are also proved to have a role in proliferation, we performed MTT assay after transient overexpression or knockdown of CASP7. Transient overexpression or knockdown of CASP7 after 48 h showed a significant change in the proliferation of breast cancer cells (Figures 10c and d, upper panels). Here, CASP7 is linked to breast cancer.