Earlier reports have demonstrated the non-apoptotic role of CASP7 targeting various cell cycle inhibitors and DNA repair proteins.36, 37 Our previous experiments showed the overexpression of CASP7 in breast carcinomas; therefore, to determine whether CASP7 affects the cell cycle, we overexpressed CASP7 (gift from Dr Jean-Bernard Denault, Université de Sherbrooke, Sherbrooke, QC, Canada) in MCF7 and T47D cells and examined the cell cycle proteins by western blot. This evidence concerns the gene CASP7 and breast carcinoma.