She was diagnosed in June 2012 with invasive lobular carcinoma of the left breast (stage IIIC, T3, pN3a, M0, GX) characterized by strongly positive estrogen receptor (ER) and progesterone receptor (PR) but human epidermal growth factor receptor 2 (HER2-neu) negative. The gene discussed is ERBB2; the disease is invasive lobular breast carcinoma.