CD4 and myocardial infarction: Furthermore, DCs act as a potent immunoprotective regulator during the post-MI healing process via DC control of the monocyte/macrophage homeostasis [54], with it being demonstrated early after MI where DCs activate not only regulatory T cells (Tregs), which are purported to prevent tissue-destructive autoimmunity after cardiac injury [56], but also other T cell subsets such as CD4+ T cells [56] and CD4+ T cells [57].