TNF and infection: Common side effects include redness, itching, pain, or swelling at the injection site (it is administered by subcutaneous injection), and because TNF-α is part of the immune system that protects the body from infection, treatment with Adalimumab may increase the risk of infections such as tuberculosis, while rarely worsening or initiation of congestive heart failure or of a multiple sclerosis/neurological disease, a lupus-like syndrome, a promotion of lymphoma, and pancytopenia have been reported [4].