Sodium Glucose Transporter-2 (SGLT-2) inhibitors, including canagliflozin, dapagliflozin, and empagliflozin, are a newer class of antidiabetic medications that are US Food and Drug Administration (FDA) approved for use with diet and exercise to lower blood sugar in adults with type 2 diabetes. Here, SLC5A2 is linked to type 2 diabetes mellitus.