As shown in Figure 1, the CLLT values for CYP1A2, 2A6, 2B6, 2C8, 2C19, and 3A4/5 in HCC patients were dramatically lower than in controls (P=2.00E-11, 7.88E-5, 1.37E-2, 8.86E-26, 1.01E-7, and 1.37E-2, respectively). This evidence concerns the gene CYP1A2 and hepatocellular carcinoma.