The melanomas used here include BRAF-mutant cells (HT144, 451Lu and MB2309), NRAS-mutated cells (WM852c, SKMEL-30, Hs852T), NF-null cells (Hs852T), or wild-type cells for the common mutations in BRAF, NRAS, or NF1 (MB2141). This evidence concerns the gene NFASC and melanoma.