One women was >65 years old, 36 did not complete or had valid data in all the physical fitness assessments, and 94 women did not met the criteria to be considered postmenopausal women (at least one year with amenorrhea and FSH > 20 mg/dL with a LH/FSH index < 0.7 or estradiol levels < 40 pg/mL). The gene discussed is PLOD1; the disease is amenorrhea.