HMG2A-NFIB fusions have been reported in lipomas while other tumour-associated translocations involving NFIB include MPDZ-NFIB, NFIB-FREM, NFIB-HEATR5B, NFIB-STRN and NFIB-ZDHHC21. The gene discussed is HEATR5B; the disease is lipoma.