The failure of trabeculectomy is mainly due to fibrosis and scar formation of subconjunctival tissue around the scleral flap and bleb during the wound-healing process.23,24 Bevacizumab, a humanized nonselective monoclonal antibody against vascular endothelial growth factor (VEGF), has been successfully used for diabetic retinopathy (DR),25 neovascular glaucoma,26,27 may work in some ways. This evidence concerns the gene VEGFA and diabetic retinopathy.