Similarly, the distribution of genotypes of the WNK1 variant rs1468326 was significantly different in HYP and NT controls, both in an additive (P = 0.0009) and a recessive model (P = 0.001), with a 2-fold increase in prevalence of the rare AA genotype in HYP (5.5% vs 2.3%) (Table 3). Here, WNK1 is linked to X-linked dominant hypophosphatemic rickets.