OTOF and Hodgkins lymphoma: Notably, mutations c.1103_1104delinsC (p.G368AfsX2), c.1180dupG (p.E394GfsX6), c.1194T>A (p.D398E), and c.1236delC (p.E413NfsX90) located in the same region of the OTOF protein have been earlier reported in patients with severe-profound HL [59–61].