By analyzing overlapping genes with the calculated 784 genes (Supplementary Table S2) in ovarian tumor stroma and 468 genes (Supplementary Table S3) in breast tumor stroma that significantly upregulated compared with their normal fibroblast counterparts in GSE40595 and breast stromal profile GSE9014, we identified ARID4B, COL3A1 and MARCKS as candidate targets for controlling stromal activation (Figure 1A). This evidence concerns the gene ARID4B and breast neoplasm.