Secretoglobin, family 1A, member 1(SCGB1A1) gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects inthis gene are associated with a susceptibility to asthma. This evidence concerns the gene SCGB1A1 and asthma.