While ΔNp63α, FAT2 and Slug are not likely druggable targets, the further delineation of signaling pathways that regulate ΔNp63α expression, or the determination of which proteins are regulated by Slug and FAT2 to promote invasion, may reveal targetable intervention points that have the potential to increase the survival time of some BLBC, NSCLC and bladder cancer patients. The gene discussed is SNAI2; the disease is non-small cell lung carcinoma.