Apart from the influence of DUOX1, GLS2 and FBP1 on prognosis of HCC patients, relationships between other clinical factors and prognosis was fuzzily confirmed by Fisher’s exact test, the results was summarized in Table 1, which showed that HBsAg expression was significantly correlated with recurrence (p = 0.014) and death (p = 0.034). The gene discussed is DUOX1; the disease is hepatocellular carcinoma.