In this regard, whilst GLP-1(9–36) did not affect the marked myocardial infiltration of CD45+ leukocytes associated with MI, increased numbers of F4/80+ macrophages, which are particularly prevalent in the ischaemic heart [18, 38], were normalised by GLP-1(9–36). The gene discussed is PTPRC; the disease is myocardial infarction.