CRP and coronary artery disorder: While the allele 2 showed its protective nature in a couple of studies,[42, 43] it also has been implicated as a risk factor for CAD in one published study.[28] Latkovskis et al.,[47] reported that presence of allele 2 in a genotype is associated with lower CRP values which can explain its protective nature seen amongst several ethnic populations.[42, 43] Genetic variation in different ethnic populations coupled with different environmental factors may account for contrasting results seen the resultant phenotypes.