IL1B and coronary artery disorder: Taking the above facts into consideration, our primary aim was to test the association of various known polymorphisms of the IL-1 gene cluster, namely: IL1A-889 C>T (rs1800587), IL1A+4845 G>T (rs17561), IL1B-1903 C>T (rs1143627), IL1B-3954 C>T (rs1143634), IL1B-5887 C>T(rs1143633), IL1B-511 C>T (rs16944), IL1RN+9589 A>T (rs454078), IL1RN+8006 T>C (rs419598), IL1RN+8061 C>T (rs423904), IL1RN+111000 T>C (rs315952) and IL1RN 86bp VNTR (PMID 14563376) and their role in the pathogenesis of CAD amongst subjects belonging to North Indian ancestry.