These include BRI3BP, shown to induce tumorigenesis through p53 stabilization [53], a putative peptidylprolyl isomerase (PPIase, PPWD1) that accelerates the folding of proteins and may be involved in pre-mRNA splicing [54], and gelsolin, expression levels of which were decreased several fold, as found for several cancer types, including U937, human myelomonocytic leukemia cell line, cervical and breast cancers. The gene discussed is BRI3BP; the disease is breast cancer.