In this analysis, we calculated sensitivity (predicted CLL patients/total CLL patients) and specificity (predicted healthy individuals/total healthy donors) values, based on VDAC1, SMAC/Diablo, Bcl-2 and MAVS (Fig 6), and for AIF, HK-I or Bax expression levels (S5 Fig). The gene discussed is MAVS; the disease is B-cell chronic lymphocytic leukemia.