LDHA and cancer: We next examined the byproduct of anaerobic glycolysis, lactate, in the HDACi-CSCs from ALDH− and ALDH+ populations and differentiated subpopulations and found that lactate production was not different in the pretreated cells versus their controls and in the stem-like cells versus committed cancer cells (p > 0.05, Figure 1G, 1H, 1I).