IGHE and asthma: T-helper type 2 cells [Th2] are recognised as an important underlying mechanism of a specific asthma phenotype that is associated with high levels of circulating IgE and atopy, and eosinophilia [4, 5] The presence of eosinophils in sputum samples has been known to be associated with asthma and has been used to indicate a good therapeutic response to inhaled or oral corticosteroid therapy [6, 7].