Our predicted NFκB pathway suggested 8 novel genes which were found to be highly down-regulated in lethal prostate cancer and highly functionally related to NFκB, namely ATF3, CXCL2, DUSP5, JUNB, NEDD9, SELE, TRIB1, and ZFP36 (Table 1). This evidence concerns the gene ATF3 and prostate carcinoma.