RELA and infection: The NFκB complex consists of 5 proteins [NFκB1 (p105), NFκB2 (p100), RELA (p65), RELB and REL (c-Rel)] and, upon activation, provides a powerful defense mechanism against infection and stress; regulation of the complex in managed in part by families of NFκB inhibitor genes (IκB) and kinases (IKK) [4,7].