TF and Tangier disease: He found in a cohort of 628 biopsy-proven NAFLD with hyperferritinemia that ferritin, besides being significantly associated with markers of liver damage (elevated serum ALT, AST and decreased platelets) and of iron overload (iron, transferrin-iron saturation and iron stain grade), was associated with more severe histologic features of NAFLD, including steatosis, hepatocellular ballooning, increased NAFLD Activity Score (NAS) and diagnosis of NASH.