We previously demonstrated that MM cells secrete EETs into the supernatant and that the CYP epoxygenase pathway participates in the MM cell-induced angiogenesis, which can be inhibited by 17-octadecynoic acid (17-ODYA), an inhibitor of CYP epoxygenase pathway (Shao et al., 2011). This evidence concerns the gene PPIG and Miyoshi myopathy.