IL33 and gastric cancer: The results showed that IL-33 expression was relatively higher in cancerous tissues (mean IHS, 3.37 ± 1.02; IHS range, 1–4) than in normal tissues (mean IHS, 2.46 ± 1.07; IHS range, 1–4) (P < 0.001) (Fig. 2a,b), indicating that IL-33 expression was up-regulated in GC and was associated with gastric tumorigenesis.